Two Sigma Ventures

Company Overview

Terray Therapeutics is a venture-backed biotechnology company led by pioneers and long-time leaders in artificial intelligence, synthetic chemistry, automation, and nanotechnology. We’re generating chemical data purpose-built to propel drug discovery into the information age — and we’re doing it on a larger scale and faster than has ever before been possible.

Our closed loop system generates precise chemical datasets at unrivaled scale that work seamlessly with AI to systematically map biochemical interactions between small molecules and causes of disease. Iterative cycles of virtual molecular design and experimentation power AI and machine learning models, which in turn guide the next cycle of design. With a chemistry engine that measures billions of interactions daily and becomes increasingly precise with every cycle, we can answer an unprecedented array of questions — deriving insights that enable us to predictably create drugs for patients in need.

Position Summary

Terray is currently seeking a motivated, creative, and experienced data scientist. As an integral member of our Computational and Data Sciences (CDS) team, the candidate will be responsible for analyzing hundreds of millions target-ligand binding interactions from our proprietary tArray platform, effectively communicating insights to teams across the company, and supporting decisions in our molecular design process with strong data acumen.

The core responsibilities of this position are:

• Develop scalable, in-house tools for clustering, molecule similarity, feature generation, SAR analysis, etc.
• Analyze binding data from our proprietary screening platform to identify hits and produce additional insights to guide molecular design.
• Effectively summarize and communicate analysis outcomes to teams across the company
• Collaborate with medicinal chemistry and molecular design to prioritize hits for resynthesis and follow-up assays

Experience and Qualifications

Part of Terray’s success is nurtured by a hands-on work environment where everyone is accountable, vested in a vision of excellence, and actively taking part in the success of the business. Terray supports a positive work environment where employees can feel engaged, recognized and empowered to be creative.

Required Qualifications

• BS/MS/PhD in computational chemistry, cheminformatics, medicinal chemistry or a related field
• Proficiency in Linux environment, experience with database languages, and experience with version control practices and tools
• Highly proficient in Python and the PyData stack (numpy, pandas, scipy, scikit-learn, etc.)
• Highly proficient in creating data visualizations in Python (matplotlib, seaborn, plotly) and/or dashboarding software (Vortex, Spotfire, Tableau)
• Experience with RDKit or related cheminformatics software (Daylight, OEChem, OpenBabel, etc.)

Compensation Details

$120,000-$180,000 (annually) depending on seniority; participation in the Company's option plan; 3% 401K contribution; full benefits.